HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 142-242) Antikörper

Produktnummer ABIN872606

Der Kaninchen Polyklonal Anti--Antikörper wurde für ELISA, IHC (p), IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 142-242) Antikörper (ABIN872606)

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails

Bindungsspezifität: AA 142-242

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIP30

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Andere Bezeichnung: TIP30

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: 30 kDa HIV 1 TAT interacting protein, 30 kDa HIV-1 TAT-interacting protein, 30 kDa HIV1 TAT interacting protein, CC3, HIV 1 Tat interacting protein 2 30 kDa, HIV 1 Tat interacting protein 2, HIV-1 Tat interacting protein 2 30 kDa, HIV-1 TAT-interactive protein 2, HTAI2_HUMAN, HTATIP 2, HTATIP2, HTATIP2, Oxidoreductase HTATIP2, SDR44U1, Short chain dehydrogenase/reductase family 44U member 1, Tat interacting protein 30 kDa, Tat-interacting protein 30 kDa.

Background: Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.Tissue specificity: Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain.

Gen-ID: 10553