DNASE2 Antikörper (AA 25-90)

Produktnummer ABIN872658

Produktdetails anti-DNASE2 Antikörper

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Bindungsspezifität: AA 25-90

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNase II alpha

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-DNASE2 Antikörper (ABIN872658)

Takahashi, Loo, Okada, Kamachi, Watanabe, Wakita, Watanabe, Kawamoto, Miyata, Barber, Ohtani, Hara: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).

Details zu DNASE2

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Andere Bezeichnung: DNase 2 alpha (DNASE2 Produkte)

Synonyme: CG7780 antikoerper, DNase antikoerper, DNase 1 antikoerper, DNase-1 antikoerper, DNase1 antikoerper, Dmel\\CG7780 antikoerper, dDNase II antikoerper, dnase2 antikoerper, MGC80103 antikoerper, DNASE2 antikoerper, LOC733868 antikoerper, fa92d01 antikoerper, wu:fa56d08 antikoerper, wu:fa92d01 antikoerper, DDBDRAFT_0188966 antikoerper, DDBDRAFT_0252883 antikoerper, DDB_0188966 antikoerper, DDB_0252883 antikoerper, Dnase2 antikoerper, DNASE2A antikoerper, DNL antikoerper, DNL2 antikoerper, Dnase2a antikoerper, Deoxyribonuclease II antikoerper, deoxyribonuclease II, lysosomal L homeolog antikoerper, deoxyribonuclease 2, lysosomal antikoerper, deoxyribonuclease II, lysosomal antikoerper, deoxyribonuclease II antikoerper, deoxyribonuclease II alpha antikoerper, DNaseII antikoerper, dnase2.L antikoerper, DNASE2 antikoerper, dnase2 antikoerper, Dnase2a antikoerper, Dnase2 antikoerper

Hintergrund:

Synonyms: DNL, DNL2, DNASE2A, Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II, R31240_2, DNASE2

Background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Gen-ID: 1777

UniProt: O00115