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DNASE2 Antikörper (AA 25-90)

Name: DNASE2 Antikörper (AA 25-90)
SKU: ABIN872658
Price: 384.62 EUR
Availability: InStock

DNASE2 Reaktivität: Human, Maus ELISA, IF (cc), IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Paraformaldehyde-fixed, paraffin embedded mouse stomach tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-DNase II Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (DNASE2 Antikörper (AA 25-90))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded mouse kidney tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-DNase II Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (DNASE2 Antikörper (AA 25-90))

IHC (p)

Formalin-fixed and paraffin embedded human laryngocarcinoma labeled with Anti-DNase II Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (DNASE2 Antikörper (AA 25-90))

IHC (p)

Human colon cancer 4% Paraformaldehyde-fixed and paraffin-embedded. (DNASE2 Antikörper (AA 25-90))

IF (p)

5 Abbildungen

(1 reference)

Produktnummer ABIN872658

Datenblatt (PDF)

Target Alle DNASE2 Antikörper anzeigen

DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))
Bindungsspezifität
14

5

4

3

2

1

1

1
AA 25-90
Reaktivität
37

20

2
Human, Maus
Wirt
35

3
Kaninchen
Passende Sekundärantikörper
Klonalität
38
Polyklonal
Konjugat
12

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser DNASE2 Antikörper ist unkonjugiert
Applikation
14

13

12

12

4

4

2

1

1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität

Human, Maus

Homologie

Rat,Dog,Cow,Sheep,Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human DNase II alpha

Isotyp

IgG
anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 19-152) antibody
DNASE2 Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 261-360) antibody
DNASE2 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 1-360) antibody
DNASE2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 1-360) antibody
DNASE2 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 347-360) antibody
DNASE2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 19-152) antibody (Biotin)
DNASE2 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 19-152) antibody (HRP)
DNASE2 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 19-152) antibody (FITC)
DNASE2 Reaktivität: Human Wirt: Kaninchen Polyclonal FITC

anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 201-300) antibody
DNASE2 Reaktivität: Human, Maus ELISA, WB Wirt: Kaninchen Polyclonal unconjugated

anti-Deoxyribonuclease II, Lysosomal (DNASE2) antibody
DNASE2 Reaktivität: Human, Maus, Ratte ELISA, WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Takahashi, Loo, Okada, Kamachi, Watanabe, Wakita, Watanabe, Kawamoto, Miyata, Barber, Ohtani, Hara: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).
Target

DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Andere Bezeichnung

DNase 2 alpha (DNASE2 Produkte)

Hintergrund

Synonyms: DNL, DNL2, DNASE2A, Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II, R31240_2, DNASE2
Background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Gen-ID

1777

UniProt

O00115