HAX1 Antikörper (AA 191-279)

Produktnummer ABIN872663

Produktdetails anti-HAX1 Antikörper

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Bindungsspezifität: AA 191-279

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HAX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Andere Bezeichnung: HAX1 (HAX1 Produkte)

Synonyme: HAX1 antikoerper, hax1 antikoerper, HCLSBP1 antikoerper, HS1BP1 antikoerper, SCN3 antikoerper, HAX-1 antikoerper, Hs1bp1 antikoerper, HSP1BP-1 antikoerper, SIG-111 antikoerper, Silg111 antikoerper, mHAX-1s antikoerper, HCLS1 associated protein X-1 antikoerper, HCLS1 associated X-1 antikoerper, HAX1 antikoerper, hax1 antikoerper, Hax1 antikoerper

Hintergrund:

Synonyms: HAX 1, Hax1a, HCLS1 and PKD2 associated protein, HCLS1 associated protein, HCLS1 associated protein X 1, HCLSBP1, HS 1 associated protein X 1, HS 1 binding protein, HS1 associating protein X 1, HS1 binding protein 1, HS1 binding protein, HS1BP1, SCN3.

Background: RelevanceHAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.

Gen-ID: 10456

Pathways: Regulation of Actin Filament Polymerization