FAM21C Antikörper (AA 1201-1318)

Produktnummer ABIN872706

Produktdetails anti-FAM21C Antikörper

Target: FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))

Bindungsspezifität: AA 1201-1318

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM21C Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM21C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FAM21C

Target: FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))

Andere Bezeichnung: Fam21c (FAM21C Produkte)

Synonyme: Fam21 antikoerper, NP61201 antikoerper, FAM21A antikoerper, VPEF antikoerper, A130095H06 antikoerper, C530005J20Rik antikoerper, D6Wsu116e antikoerper, fam21c antikoerper, wu:fb78c06 antikoerper, zgc:153646 antikoerper, WASH complex subunit 2C antikoerper, WASH complex subunit 2 antikoerper, family with sequence similarity 21, member C antikoerper, Washc2c antikoerper, WASHC2C antikoerper, Washc2 antikoerper, washc2c antikoerper

Hintergrund:

Synonyms: FAM21A, Family with sequence similarity 21 member C, Hypothetical protein LOC253725, KIAA0592, Protein FAM21C, FA21C_HUMAN.

Background: Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.

Gen-ID: 253725