GIMAP5 Antikörper (AA 101-200)

Produktnummer ABIN872708

Produktdetails anti-GIMAP5 Antikörper

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GIMAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIMAP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GIMAP5

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Andere Bezeichnung: Gimap5 (GIMAP5 Produkte)

Synonyme: HIMAP3 antikoerper, IAN-5 antikoerper, IAN4 antikoerper, IAN4L1 antikoerper, IAN5 antikoerper, IMAP3 antikoerper, IROD antikoerper, Ian4l1 antikoerper, Ian5 antikoerper, D630024P16 antikoerper, E230026N22Rik antikoerper, GTPase, IMAP family member 5 antikoerper, GTPase IMAP family member 5 antikoerper, GIMAP5 antikoerper, Gimap5 antikoerper, LOC463896 antikoerper

Hintergrund:

Synonyms: HIMAP3, IAN4, IAN4L1, IAN5, IMAP3, FLJ11296, GIMAP 5, GTPase IMAP family member 5, GTPase, IMAP family member 5, immunity-associated nucleotide 5, hIAN5, IAN 5, Immune associated nucleotide 4 like 1, Immunity associated nucleotide 4 like 1 protein, Immunity associated protein 3, GIMA5_HUMAN.

Background: GIMAP5, also known as IAN5, IAN4L1 (immunity-associated nucleotide 4-like 1 protein), IAN4, IMAP3, HIMAP3 or IROD, is a 307 amino acid single-pass type IV membrane protein of the mitochondrial outer membrane. A member of the GTP-binding superfamily and the immuno-associated nucleotide (IAN) subfamily, GIMAP5 plays a role in T-cell survival and mitochondrial integrity. GIMAP5 is highly expressed in CD4 and CD8-positive T-cells and monocytes, as well as B-lymphocyte-derived neoplasms. GIMAP5 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 7q36.1. Defects in the GIMAP5 gene are associated with systemic lupus erythematosus.

Gen-ID: 55340

UniProt: Q96F15

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response