SKA3 Antikörper (AA 201-300)

Produktnummer ABIN872869

Produktdetails anti-SKA3 Antikörper

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Bindungsspezifität: AA 201-300

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKA3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SKA3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SKA3 Antikörper (ABIN872869)

Hou, Wang, Huang, Sun, Zhao, Shi, Li, Wang, He, Tam, Wu: "SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma." in: Cell death & disease, Vol. 10, Issue 12, pp. 929, (2020) (PubMed).

Details zu SKA3

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Andere Bezeichnung: SKA3 (SKA3 Produkte)

Synonyme: C13orf3 antikoerper, RAMA1 antikoerper, RGD1307201 antikoerper, C12H13ORF3 antikoerper, fc23d11 antikoerper, si:rp71-68n21.13 antikoerper, wu:fc23d11 antikoerper, rama1 antikoerper, F630043A04Rik antikoerper, spindle and kinetochore associated complex subunit 3 antikoerper, spindle and kinetochore associated complex subunit 3 L homeolog antikoerper, SKA3 antikoerper, Ska3 antikoerper, ska3 antikoerper, ska3.L antikoerper

Hintergrund:

Synonyms: C13orf3, RAMA1, SKA3, SKA3_HUMAN, Spindle and kinetochore associated complex subunit 3, Spindle and kinetochore-associated protein 3.

Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.