FGG Antikörper (AA 151-250)

Produktnummer ABIN872908

Produktdetails anti-FGG Antikörper

Target: FGG (Fibrinogen gamma Chain (FGG))

Bindungsspezifität: AA 151-250

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Fibrinogen gamma chain

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-FGG Antikörper (ABIN872908)

Li, He, Di, Yan, Zhang: "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." in: Life sciences, Vol. 167, pp. 57-66, (2016) (PubMed).

Details zu FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Andere Bezeichnung: Fibrinogen gamma chain (FGG Produkte)

Synonyme: FXII antikoerper, HAF antikoerper, 3010002H13Rik antikoerper, AI256424 antikoerper, fibrinogen antikoerper, FGG antikoerper, LOC100220680 antikoerper, fb60h05 antikoerper, fb62e01 antikoerper, wu:fb60h05 antikoerper, wu:fb62e01 antikoerper, zgc:56023 antikoerper, fibrinogen gamma chain antikoerper, coagulation factor XII (Hageman factor) antikoerper, fibrinogen gamma chain L homeolog antikoerper, FGG antikoerper, F12 antikoerper, fgg antikoerper, Fgg antikoerper, fgg.L antikoerper, CpipJ_CPIJ006387 antikoerper, CpipJ_CPIJ010087 antikoerper

Hintergrund:

Synonyms: Fibrinogen gamma chain, FGG, PRO2061

Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Gen-ID: 2266

UniProt: P02679