IKZF1 Antikörper (AA 251-360)

Produktnummer ABIN872958

Produktdetails anti-IKZF1 Antikörper

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Bindungsspezifität: AA 251-360

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKZF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IKAROS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IKZF1

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Andere Bezeichnung: Ikaros (IKZF1 Produkte)

Synonyme: Hs.54452 antikoerper, IK1 antikoerper, IKAROS antikoerper, LYF1 antikoerper, PRO0758 antikoerper, ZNFN1A1 antikoerper, hIk-1 antikoerper, RGD1562979 antikoerper, ikaros antikoerper, znfn1a1 antikoerper, ik1 antikoerper, lyf1 antikoerper, hik-1 antikoerper, pro0758 antikoerper, hs.54452 antikoerper, MGC108252 antikoerper, 5832432G11Rik antikoerper, Ikaros antikoerper, LyF-1 antikoerper, Zfpn1a1 antikoerper, Znfn1a1 antikoerper, hlk-1 antikoerper, mKIAA4227 antikoerper, ikzf1 antikoerper, IKAROS family zinc finger 1 antikoerper, IKAROS family zinc finger 1 (Ikaros) antikoerper, IKZF1 antikoerper, Ikzf1 antikoerper, ikzf1 antikoerper

Hintergrund:

Synonyms: IKAROS family zinc finger 1 Ikaros, PRO0758, CLL associated antigen KW 6, DNA-binding protein Ikaros, hIk 1, hIk-1, IK1, Ikaros zinc finger protein, IKAROS, Ikaros family zinc finger protein 1, Ikzf1, IKZF1_HUMAN, LYF1, Lymphoid transcription factor LyF-1, zinc finger protein subfamily 1A 1, ZNFN1A1.

Background: Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).Tissue specificity:Abundantly expressed in thymus, spleen and peripheral blood Leukocytes and lymph nodes. Lower expression in bone marrow and small intestine.

Gen-ID: 10320

Pathways: Production of Molecular Mediator of Immune Response