RBPJ Antikörper (AA 101-200)
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- Target Alle RBPJ Antikörper anzeigen
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
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Bindungsspezifität
- AA 101-200
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RBPJ Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RBPJK
- Isotyp
- IgG
- Top Product
- Discover our top product RBPJ Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
- Andere Bezeichnung
- RBPJK (RBPJ Produkte)
- Synonyme
- AOS3 antikoerper, CBF1 antikoerper, IGKJRB antikoerper, IGKJRB1 antikoerper, KBF2 antikoerper, RBP-J antikoerper, RBPJK antikoerper, RBPSUH antikoerper, SUH antikoerper, csl antikoerper, AI843960 antikoerper, Igkjrb antikoerper, Igkrsbp antikoerper, RBP-J kappa antikoerper, RBPjk antikoerper, Rbpsuh antikoerper, Su(H) antikoerper, XSu(H) antikoerper, xsu(h)1 antikoerper, Su(H)1 antikoerper, Su(h)A antikoerper, ik:tdsubc_1e8 antikoerper, rbpj antikoerper, rbpsuh antikoerper, xx:tdsubc_1e8 antikoerper, Su(H)2 antikoerper, su(h)B antikoerper, recombination signal binding protein for immunoglobulin kappa J region antikoerper, recombination signal binding protein for immunoglobulin kappa J region S homeolog antikoerper, recombination signal binding protein for immunoglobulin kappa J region a antikoerper, recombination signal binding protein for immunoglobulin kappa J region b antikoerper, RBPJ antikoerper, Rbpj antikoerper, rbpj.S antikoerper, rbpja antikoerper, rbpjb antikoerper
- Hintergrund
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Synonyms: SUH, csl, AOS3, CBF1, KBF2, RBP-J, RBPJK, IGKJRB, RBPSUH, IGKJRB1, Recombining binding protein suppressor of hairless, CBF-1, J kappa-recombination signal-binding protein, RBP-J kappa, RBP-JK, Renal carcinoma antigen NY-REN-30, RBPJ
Background: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
- Gen-ID
- 3516
- UniProt
- Q06330
- Pathways
- Notch Signalweg, Stem Cell Maintenance, Smooth Muscle Cell Migration
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