CLK2 Antikörper (AA 401-499)

Produktnummer ABIN873014

Produktdetails anti-CLK2 Antikörper

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Bindungsspezifität: AA 401-499

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Andere Bezeichnung: CLK2 (CLK2 Produkte)

Synonyme: MGC53993 antikoerper, hclk2 antikoerper, clk2 antikoerper, fb20c02 antikoerper, si:ch211-81a5.7 antikoerper, wu:fb20c02 antikoerper, MGC131228 antikoerper, hCLK2 antikoerper, AU041688 antikoerper, Tu52 antikoerper, CDC like kinase 2 antikoerper, CDC like kinase 2 S homeolog antikoerper, CDC-like kinase 2a antikoerper, CDC like kinase 2 L homeolog antikoerper, CDC-like kinase 2 antikoerper, CLK2 antikoerper, clk2.S antikoerper, clk2 antikoerper, clk2a antikoerper, clk2.L antikoerper, Clk2 antikoerper

Hintergrund:

Synonyms: CDC like kinase 2, CLK 2, CLK kinase, Clk2 Scamp3, Dual specicity protein kinase CLK2, hCLK 2, hCLK2, MGC61500, Tu52, CLK2_HUMAN.

Background: CDC-like kinase 2 (CLK2) belongs to a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases), which have been shown to phosphorylate serine- and arginine-rich (SR) proteins of the spliceosomal complex, and to influence alternative splicing in overexpression systems. Recent findings demonstrated that the CLK kinases activate PTP-1B family members, and this phosphatase may be an important cellular target for CLK action. Mutations in the CLK2 proteins affect organismal features such as development, behavior, reproduction, and aging as well as cellular features such as the cell cycle, apoptosis, the DNA replication checkpoint, and telomere length.

Gen-ID: 1196

Pathways: Regulation of Carbohydrate Metabolic Process