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GGT1 Antikörper (AA 351-460)

GGT1 Reaktivität: Human WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN873023
  • Target Alle GGT1 Antikörper anzeigen
    GGT1 (gamma Glutamyltransferase 1 (GGT1))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-460
    Reaktivität
    • 68
    • 33
    • 17
    • 6
    Human
    Wirt
    • 63
    • 13
    • 1
    Kaninchen
    Klonalität
    • 66
    • 11
    Polyklonal
    Konjugat
    • 35
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GGT1 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 29
    • 21
    • 13
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GGT1
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GGT1 (gamma Glutamyltransferase 1 (GGT1))
    Andere Bezeichnung
    GGT1 (GGT1 Produkte)
    Hintergrund

    Synonyms: GGT, GTG, CD224, GGT 1, D22S672, D22S732, Gamma-glutamyltranspeptidase 1, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, Leukotriene-C4 hydrolase, GGT1

    Background: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.

    Gen-ID
    2678
    UniProt
    P19440
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