A1CF Antikörper (AA 101-200)

Produktnummer ABIN873052

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch A1CF in IHC (p), IF (cc), IF (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für A1CF Antikörper (AA 101-200) (ABIN873052)

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A1CF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-A1CF Antikörper

Bindungsspezifität: AA 101-200

Verwendungszweck: A1CF Polyclonal Antibody

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human A1CF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu A1CF

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Andere Bezeichnung: A1CF

Hintergrund:

Synonyms: A1CF, A1CF_HUMAN, ACF, ACF64, ACF65, Apo B RNA editing protein, Apobec 1 complementation factor, Apobec 1 complementation factor ACF ASP, APOBEC 1 stimulating protein, APOBEC1 complementation factor, APOBEC1 stimulating protein, APOBEC1-stimulating protein, APOBEC1CF, ASP, MGC163391, RP11-564C4.2.

Background: Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.

Gen-ID: 29974