KLHL21 Antikörper (AA 51-110)

Produktnummer ABIN873084

Produktdetails anti-KLHL21 Antikörper

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Bindungsspezifität: AA 51-110

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLHL21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHL21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu KLHL21

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Andere Bezeichnung: KLHL21 (KLHL21 Produkte)

Synonyme: zgc:76933 antikoerper, 1810045K06Rik antikoerper, D330008A20 antikoerper, mKIAA0469 antikoerper, RGD1305863 antikoerper, kelch-like family member 21 antikoerper, kelch like family member 21 antikoerper, kelch like family member 21 L homeolog antikoerper, kelch-like 21 antikoerper, klhl21 antikoerper, KLHL21 antikoerper, klhl21.L antikoerper, Klhl21 antikoerper

Hintergrund:

Synonyms: Kelch like protein 21, KIAA0469, KLHL21, MGC99635, KLH21_HUMAN.

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

Gen-ID: 9903

Pathways: M Phase