SART1 Antikörper (AA 701-800)

Produktnummer ABIN873218

Produktdetails anti-SART1 Antikörper

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Bindungsspezifität: AA 701-800

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SART1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SART1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SART1

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Andere Bezeichnung: SART1 (SART1 Produkte)

Synonyme: Dmel\\CG6686 antikoerper, SART1 antikoerper, MGC53679 antikoerper, MGC132129 antikoerper, zgc:91927 antikoerper, Ara1 antikoerper, HOMS1 antikoerper, SART1259 antikoerper, SNRNP110 antikoerper, Snu66 antikoerper, U5-110K antikoerper, CG6686 gene product from transcript CG6686-RB antikoerper, SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog antikoerper, SART1, U4/U6.U5 tri-snRNP-associated protein 1 antikoerper, squamous-cell carcinoma T-cell-recognized antigen antikoerper, squamous cell carcinoma antigen recognized by T cells 1 antikoerper, CG6686 antikoerper, sart1.S antikoerper, sart1 antikoerper, SART1 antikoerper, Sart1 antikoerper

Hintergrund:

Synonyms: Ara 1, ARA1, HOMS 1, HOMS1, hSART 1, hSART1, hSnu 66, hSnu66, IgE autoantigen, MGC2038, SART 1, SART1 259, SART1259 protein, SART1800 protein, SART1259, Snu 66, Snu66, Squamous cell carcinoma antigen recognised by T cells, Squamous cell carcinoma antigen recognized by T cells 1, U4/U6.U5 tri snRNP associated 110 kDa protein, U4/U6.U5 tri snRNP associated protein, SNUT1_HUMAN.

Background: SART1 encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri snRNP to the pre spliceosome in the spliceosome assembly pathway.

Gen-ID: 9092

Pathways: Ribonucleoprotein Complex Subunit Organization