BMP1 Antikörper

Produktnummer ABIN873233

Produktdetails anti-BMP1 Antikörper

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BMP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu BMP1

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Andere Bezeichnung: Bmp1 (BMP1 Produkte)

Synonyme: OI13 antikoerper, PCOLC antikoerper, PCP antikoerper, PCP2 antikoerper, TLD antikoerper, Pcp antikoerper, Tld antikoerper, BMP1 antikoerper, submp antikoerper, tld antikoerper, xtld antikoerper, bmp-1 antikoerper, pcolc antikoerper, xbmp1 antikoerper, tolloid antikoerper, BMP-1 antikoerper, bmp1 antikoerper, bmp1a antikoerper, bone morphogenetic protein 1 antikoerper, Bone morphogenetic protein 1 antikoerper, bone morphogenetic protein 1 S homeolog antikoerper, bone morphogenetic protein 1, like antikoerper, BMP1 antikoerper, Bmp1 antikoerper, bmp1 antikoerper, bmp1.S antikoerper, bmp1l antikoerper

Hintergrund:

Synonyms: BMP 1, BMP-1, Bone morphogenetic protein 1, Mammalian tolloid protein, mTld, PCOLC, PCP, ProCollagen C endopeptidase, Procollagen C proteinase, TLD, BMP1_HUMAN.

Background: Bone morphogenetic protein 1 (BMP1) was first identified in osteogenic extracts of bone. It is an extracellular zinc endopeptidase, implicated in morphogenetic processes in a broad range of species. BMP1 is a member of the astacin family of metalloproteinases. The astacin family includes BMP1, astacin, meprin A and B, tolloid-like proteins, and choriolysin. BMP1 is involved in extracellular matrix (ECM) formation, suggesting that a functional link may exist between astacin metalloproteinases, growth factors, and cell differentiation and pattern formation during development. The name PCP reflects this enzyme’s involvement in the collagen deposition of growing bone. The enzymes known as the procollagen C and N proteinases (PCP and PNP) are involved in the processing of fibrillar procollagen precursors to mature collagens, which is an essential requirement for fibril formation. PCP cleaves the C-terminus from procollagen, to allow the formation of mature, triplehelical collagen. The N-terminus is cleaved by the procollagen N-proteinase (PNP or ADAM-TS2). Defects in PNP have been linked to the skin disorder dermatosparaxis, and defects in BMP1 are thought to lead to aberrant collagen processing, and connective tissue disorders. Many forms of BMP1 have been reported, with varying truncation at the C-terminus. The long form of BMP1 is most similar to the tolloid-like proteins, which have extra EGF-like and CUB domains.

Gen-ID: 649

Pathways: Lipid Metabolism