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CCDC116 Antikörper (AA 155-260)

CCDC116 Reaktivität: Human ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN873296
  • Target Alle CCDC116 Antikörper anzeigen
    CCDC116 (Coiled-Coil Domain Containing 116 (CCDC116))
    Bindungsspezifität
    • 8
    • 4
    • 1
    • 1
    AA 155-260
    Reaktivität
    • 11
    • 1
    • 1
    Human
    Wirt
    • 11
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 5
    • 2
    • 2
    • 2
    Dieser CCDC116 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CCDC116
    Isotyp
    IgG
    Top Product
    Discover our top product CCDC116 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CCDC116 (Coiled-Coil Domain Containing 116 (CCDC116))
    Andere Bezeichnung
    CCDC116 (CCDC116 Produkte)
    Synonyme
    MGC134460 antikoerper, 4930432J16Rik antikoerper, Sdf2l1 antikoerper, coiled-coil domain containing 116 antikoerper, CCDC116 antikoerper, Ccdc116 antikoerper
    Hintergrund

    Synonyms: CC116_HUMAN, Ccdc116, Coiled-coil domain-containing protein 116.

    Background: CCDC116 is a 515 amino acid protein that exists as two alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 22q11.21, CCDC116 is induced by curcumin (diferulolylmethane), although its role is unclear. CCDC116 is significantly affected by dietary curcumin, which may have a protective role in inflammatory bowel disease (IBD) and may reduce the relapse rate in human ulcerative colitis (UC). As the second smallest human chromosome, chromosome 22 contains over 500 genes and about 49 million bases. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocation between chromosomes 9 and 22 may lead to the formation of Philadelphia Chromosome and subsequent production of a novel fusion protein known as BCR-Abl, a potent cell proliferation activator found in several types of leukemia.

    Gen-ID
    164592
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