ATG3 Antikörper (pTyr18) (AbBy Fluor® 555)
-
- Target Alle ATG3 Antikörper anzeigen
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
-
Bindungsspezifität
- pTyr18
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ATG3 Antikörper ist konjugiert mit AbBy Fluor® 555
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human ATG3 around the phosphorylation site of Tyr18
- Isotyp
- IgG
- Top Product
- Discover our top product ATG3 Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
- Andere Bezeichnung
- ATG3 (ATG3 Produkte)
- Synonyme
- atg3 antikoerper, im:6910145 antikoerper, wu:fb15g12 antikoerper, zgc:64156 antikoerper, APG3 antikoerper, APG3-LIKE antikoerper, APG3L antikoerper, PC3-96 antikoerper, 2610016C12Rik antikoerper, Apg3l antikoerper, Atg3l antikoerper, PIG-1 antikoerper, Pig1 antikoerper, ATATG3 antikoerper, K11J9.1 antikoerper, K11J9_1 antikoerper, autophagy related 3 antikoerper, autophagy 3 (APG3) antikoerper, similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy antikoerper, atg3 antikoerper, ATG3 antikoerper, Atg3 antikoerper
- Hintergrund
-
Synonyms: 2610016C12Rik, Apg 3, APG3, APG3 autophagy 3 like, APG3 like, APG3-like, APG3L, Apg3p, ATG 3, ATG3, ATG3 autophagy related 3 homolog, ATG3 autophagy related 3 homolog S. cerevisiae, ATG3_HUMAN, Autophagy Apg3p/Aut1p like, Autophagy related protein 3, Autophagy-related protein 3, DKFZp564M1178, FLJ22125, hApg3, MGC15201, OTTHUMP00000214547, OTTHUMP00000214548, PC3 96, Protein PC3-96, Ubiquitin-like-conjugating enzyme ATG3.
Background: E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
- Gen-ID
- 64422
- Pathways
- Autophagie
-