HNE Antikörper (Biotin)

Produktnummer ABIN880510

Produktdetails anti-HNE Antikörper (Biotin)

Target: HNE (4-Hydroxynonenal (HNE))

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNE Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Affe, Maus, Ratte

Kreuzreaktivität (Details): 4-Hydroxynonenal

Aufreinigung: Purified by Protein A.

Immunogen: 4 Hydroxynonenal conjugated to BSA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu HNE

Target: HNE (4-Hydroxynonenal (HNE))

Andere Bezeichnung: 4 Hydroxynonenal (HNE Produkte)

Substanzklasse: Chemical

Hintergrund:

Synonyms: 4-Hydroxy-2-Nonenal, 4Hydroxynonenal, 4-Hydroxynonenal, 4 HNE, 4HNE, 4-HNE, E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA.

Background: Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.