AGFG1 Antikörper (AA 276-380) (AbBy Fluor® 647)

Produktnummer ABIN881809

Produktdetails anti-AGFG1 Antikörper (AbBy Fluor® 647)

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Bindungsspezifität: AA 276-380

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGFG1 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AGFG1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu AGFG1

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Andere Bezeichnung: AGFG1 (HRB Produkte)

Hintergrund:

Synonyms: HIV 1 Rev binding protein, RAB, Rev/Rex activation domain-binding protein, RIP, AGFG1, AGFG1_HUMAN, Arf-GAP domain and FG repeats-containing protein 1, ArfGAP with FG repeats 1, HIV-1 Rev-binding protein, HRB, Nucleoporin like protein RIP, Nucleoporin-like protein RIP, Rev interacting protein, Rev-interacting protein.

Background: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.