ALOXE3 Antikörper (AA 141-240) (AbBy Fluor® 488)

Produktnummer ABIN882264

Produktdetails anti-ALOXE3 Antikörper (AbBy Fluor® 488)

Target: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Bindungsspezifität: AA 141-240

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOXE3 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ALOXE3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ALOXE3

Target: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Andere Bezeichnung: ALOXE3 (ALOXE3 Produkte)

Synonyme: e-lox antikoerper, elox3 antikoerper, ARCI3 antikoerper, E-LOX antikoerper, eLOX3 antikoerper, e-LOX-3 antikoerper, ALOX15B antikoerper, arachidonate lipoxygenase 3 antikoerper, arachidonate lipoxygenase 3 L homeolog antikoerper, arachidonate 15-lipoxygenase, type B antikoerper, ALOXE3 antikoerper, aloxe3.L antikoerper, aloxe3 antikoerper, Aloxe3 antikoerper, ALOX15B antikoerper

Hintergrund:

Synonyms: ALOXE3, Arachidonate lipoxygenase 3, e LOX 3, E LOX, e-LOX-3, eLOX3, Epidermal lipoxygenase, Epidermis-type lipoxygenase 3, Lipoxygenase 3, LOXE3_HUMAN.

Background: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.Tissue specificity:Predominantly expressed in skin.Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.

Gen-ID: 59344

Pathways: Cell-Cell Junction Organization