ANKRD11 Antikörper (AA 731-820) (AbBy Fluor® 488)

Produktnummer ABIN882687

Produktdetails anti-ANKRD11 Antikörper (AbBy Fluor® 488)

Target: ANKRD11 (Ankyrin Repeat Domain 11 (ANKRD11))

Bindungsspezifität: AA 731-820

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD11 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKRD11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ANKRD11

Target: ANKRD11 (Ankyrin Repeat Domain 11 (ANKRD11))

Andere Bezeichnung: ANKRD11 (ANKRD11 Produkte)

Synonyme: ANCO-1 antikoerper, ANCO1 antikoerper, LZ16 antikoerper, T13 antikoerper, 2410104C19Rik antikoerper, 3010027A04Rik antikoerper, 6330578C09Rik antikoerper, 9530048I21Rik antikoerper, AA930108 antikoerper, Gm176 antikoerper, Yod antikoerper, ANKRD11 antikoerper, wu:fc59e05 antikoerper, wu:fi04c06 antikoerper, ankyrin repeat domain 11 antikoerper, ankyrin repeat domain 11 L homeolog antikoerper, ANKRD11 antikoerper, Ankrd11 antikoerper, ankrd11.L antikoerper, ankrd11 antikoerper

Hintergrund:

Synonyms: ANCO 1, ANCO1, Ankyrin repeat containing cofactor 1, Ankyrin repeat domain 11, Ankyrin repeat domain containing protein 11, LZ16, T13.

Background: Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 2224 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases, most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.

Gen-ID: 29123