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ASB3 Antikörper (AA 21-120) (Cy7)

ASB3 Reaktivität: Human, Maus IF (p), IF (cc) Wirt: Kaninchen Polyclonal Cy7
Produktnummer ABIN883756
  • Target Alle ASB3 Antikörper anzeigen
    ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 41
    • 22
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 39
    • 2
    Kaninchen
    Klonalität
    • 39
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASB3 Antikörper ist konjugiert mit Cy7
    Applikation
    • 19
    • 17
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ASB3
    Isotyp
    IgG
    Top Product
    Discover our top product ASB3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))
    Andere Bezeichnung
    ASB3 (ASB3 Produkte)
    Synonyme
    ASB-3 antikoerper, 2400011J03Rik antikoerper, Asb-3 antikoerper, fi36b12 antikoerper, zgc:56163 antikoerper, wu:fi36b12 antikoerper, ASB3 antikoerper, DKFZp459D0910 antikoerper, asb-3 antikoerper, asb3 antikoerper, ankyrin repeat and SOCS box containing 3 antikoerper, ankyrin repeat and SOCS box-containing 3 antikoerper, ankyrin repeat and SOCS box containing 3 S homeolog antikoerper, ASB3 antikoerper, Asb3 antikoerper, asb3 antikoerper, asb3.S antikoerper
    Hintergrund

    Synonyms: Ankyrin repeat and SOCS box containing 3, Ankyrin repeat and SOCS box containing protein 3, Ankyrin repeat and SOCS box protein 3, ASB-3, ASB3, ASB3_HUMAN, Weakly similar to ankyrin brain variant 2.

    Background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.

    Gen-ID
    51130
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