CCDC138 Antikörper (AA 551-665) (AbBy Fluor® 350)

Produktnummer ABIN887233

Produktdetails anti-CCDC138 Antikörper (AbBy Fluor® 350)

Target: CCDC138 (Coiled-Coil Domain Containing 138 (CCDC138))

Bindungsspezifität: AA 551-665

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC138 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC138

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCDC138

Target: CCDC138 (Coiled-Coil Domain Containing 138 (CCDC138))

Andere Bezeichnung: CCDC138 (CCDC138 Produkte)

Synonyme: 6230424H07Rik antikoerper, BC042726 antikoerper, MGC115290 antikoerper, RGD1566050 antikoerper, coiled-coil domain containing 138 antikoerper, coiled-coil domain containing 138 L homeolog antikoerper, Ccdc138 antikoerper, CCDC138 antikoerper, ccdc138.L antikoerper, ccdc138 antikoerper

Hintergrund:

Synonyms: CCDC 138, CCDC138, Coiled coil domain containing 138, Coiled coil domain containing protein 138, coiled-coil domain containing 138, FLJ 32745, FLJ32745, CC138_HUMAN.

Background: CCDC138, also known as FLJ32745, is a 685 amino acid protein expressed as two isoforms produced by alternative splicing. The gene that encodes CCDC138 maps to human chromosome 2q12.3. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Gen-ID: 165055

Pathways: BCR Signaling