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CCDC18 Antikörper (AA 55-160) (AbBy Fluor® 647)

CCDC18 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN887471
  • Target Alle CCDC18 Antikörper anzeigen
    CCDC18 (Coiled-Coil Domain Containing 18 (CCDC18))
    Bindungsspezifität
    • 14
    • 2
    AA 55-160
    Reaktivität
    • 16
    • 1
    Human
    Wirt
    • 16
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCDC18 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CCDC18
    Isotyp
    IgG
    Top Product
    Discover our top product CCDC18 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CCDC18 (Coiled-Coil Domain Containing 18 (CCDC18))
    Andere Bezeichnung
    CCDC18 (CCDC18 Produkte)
    Synonyme
    NY-SAR-41 antikoerper, dJ717I23.1 antikoerper, 1700021E15Rik antikoerper, 4932411G06Rik antikoerper, RGD1564165 antikoerper, p170 antikoerper, sojo antikoerper, sojo-A antikoerper, coiled-coil domain containing 18 antikoerper, coiled-coil domain containing 18 L homeolog antikoerper, CCDC18 antikoerper, Ccdc18 antikoerper, ccdc18.L antikoerper
    Hintergrund

    Synonyms: CCD18_HUMAN, Ccdc18, Coiled-coil domain-containing protein 18, Sarcoma antigen NY-SAR-24.

    Background: CCDC18, also known as NY-SAR-41 or dJ717I23.1, is a 1,454 amino acid protein expressed as two isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

    Gen-ID
    343099
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