CCDC18 Antikörper (AA 55-160) (AbBy Fluor® 350)

Produktnummer ABIN887478

Produktdetails anti-CCDC18 Antikörper (AbBy Fluor® 350)

Target: CCDC18 (Coiled-Coil Domain Containing 18 (CCDC18))

Bindungsspezifität: AA 55-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC18 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC18

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCDC18

Target: CCDC18 (Coiled-Coil Domain Containing 18 (CCDC18))

Andere Bezeichnung: CCDC18 (CCDC18 Produkte)

Synonyme: NY-SAR-41 antikoerper, dJ717I23.1 antikoerper, 1700021E15Rik antikoerper, 4932411G06Rik antikoerper, RGD1564165 antikoerper, p170 antikoerper, sojo antikoerper, sojo-A antikoerper, coiled-coil domain containing 18 antikoerper, coiled-coil domain containing 18 L homeolog antikoerper, CCDC18 antikoerper, Ccdc18 antikoerper, ccdc18.L antikoerper

Hintergrund:

Synonyms: CCD18_HUMAN, Ccdc18, Coiled-coil domain-containing protein 18, Sarcoma antigen NY-SAR-24.

Background: CCDC18, also known as NY-SAR-41 or dJ717I23.1, is a 1,454 amino acid protein expressed as two isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gen-ID: 343099