CCDC40 Antikörper (AA 851-950) (AbBy Fluor® 488)

Produktnummer ABIN887711

Produktdetails anti-CCDC40 Antikörper (AbBy Fluor® 488)

Target: CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))

Bindungsspezifität: AA 851-950

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC40 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCDC40

Target: CCDC40 (Coiled-Coil Domain Containing 40 (CCDC40))

Andere Bezeichnung: CCDC40 (CCDC40 Produkte)

Synonyme: CILD15 antikoerper, B930008I02Rik antikoerper, im:7149866 antikoerper, lok antikoerper, si:dkey-237i9.5 antikoerper, wu:fb11d02 antikoerper, coiled-coil domain containing 40 antikoerper, CCDC40 antikoerper, Ccdc40 antikoerper, ccdc40 antikoerper

Hintergrund:

Synonyms: CCD40_HUMAN, ccdc 40, CCDC40, Coiled coil domain containing 40, coiled-coil domain containing 40, Coiled-coil domain-containing protein 40.

Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.Involvement in disease:Defects in CCDC40 are the cause of primary ciliary dyskinesia type 15 (CILD15) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

Gen-ID: 55036