CPEB1 Antikörper (AA 451-550) (AbBy Fluor® 647)
-
- Target Alle CPEB1 Antikörper anzeigen
- CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
-
Bindungsspezifität
- AA 451-550
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CPEB1 Antikörper ist konjugiert mit AbBy Fluor® 647
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CPEB1
- Isotyp
- IgG
- Top Product
- Discover our top product CPEB1 Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
- Andere Bezeichnung
- CPEB1 (CPEB1 Produkte)
- Synonyme
- CEBP antikoerper, CPE-BP1 antikoerper, CPEB antikoerper, AU024112 antikoerper, Cpeb antikoerper, mCPEB antikoerper, CPEB1 antikoerper, cpeb1 antikoerper, ZOR-1 antikoerper, cepb1b antikoerper, fd15c06 antikoerper, wu:fd15c06 antikoerper, zorba antikoerper, cytoplasmic polyadenylation element binding protein 1 antikoerper, hypothetical protein antikoerper, cytoplasmic polyadenylation element binding protein 1 L homeolog antikoerper, cytoplasmic polyadenylation element binding protein 1b antikoerper, cytoplasmic polyadenylation element binding protein 1 S homeolog antikoerper, CPEB1 antikoerper, Cpeb1 antikoerper, cpeb1 antikoerper, LOAG_17395 antikoerper, cpeb1.L antikoerper, cpeb1b antikoerper, cpeb1.S antikoerper
- Hintergrund
-
Synonyms: CPE-binding protein 1, CPE-BP1, CPEB 1, CPEB, CPEB1, CPEB1 protein, CPEB1_HUMAN, Cytoplasmic polyadenylation binding protein 1, Cytoplasmic polyadenylation element binding protein, Cytoplasmic polyadenylation element binding protein 1, Cytoplasmic polyadenylation element-binding protein 1, h-CEBP, hCPEB-1
Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
- Gen-ID
- 64506
- Pathways
- Synaptic Membrane
-