CUBN Antikörper (AA 51-150) (AbBy Fluor® 555)
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- Target Alle CUBN Antikörper anzeigen
- CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
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Bindungsspezifität
- AA 51-150
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CUBN Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Cubilin
- Isotyp
- IgG
- Top Product
- Discover our top product CUBN Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
- Andere Bezeichnung
- Cubilin (CUBN Produkte)
- Synonyme
- GP280 antikoerper, IFCR antikoerper, MGA1 antikoerper, AA408369 antikoerper, AL022750 antikoerper, D2Wsu88e antikoerper, gp280 antikoerper, cubilin antikoerper, cubilin (intrinsic factor-cobalamin receptor) antikoerper, LOC411053 antikoerper, CUBN antikoerper, cubn antikoerper, Cubn antikoerper
- Hintergrund
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Synonyms: IFCR, MGA1, gp280, Cubilin, 460 kDa receptor, Intestinal intrinsic factor receptor, Intrinsic factor-cobalamin receptor, Intrinsic factor-vitamin B12 receptor, CUBN
Background: Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
- Gen-ID
- 8029
- UniProt
- O60494
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism
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