DBF4 Antikörper (AA 21-110) (AbBy Fluor® 488)

Produktnummer ABIN893547

Produktdetails anti-DBF4 Antikörper (AbBy Fluor® 488)

Target: DBF4 (DBF4 Homolog (DBF4))

Bindungsspezifität: AA 21-110

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DBF4 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DBF4A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DBF4

Target: DBF4 (DBF4 Homolog (DBF4))

Andere Bezeichnung: DBF4A (DBF4 Produkte)

Synonyme: ASK antikoerper, CHIF antikoerper, DBF4A antikoerper, ZDBF1 antikoerper, RGD1305854 antikoerper, DBF4 antikoerper, LOC100229596 antikoerper, AA545217 antikoerper, Ask antikoerper, dbf4a antikoerper, xdbf4 antikoerper, ChDBF4 antikoerper, DBF4 zinc finger antikoerper, DBF4 zinc finger L homeolog antikoerper, DBF4 antikoerper, dbf4 antikoerper, Dbf4 antikoerper, dbf4.L antikoerper

Hintergrund:

Synonyms: Activator of S phase kinase, ASK, Chfon homolog A, DBF4, DBF4 type zinc finger containing protein 1, DBF4-type zinc finger-containing protein 1, DBF4A, DBF4A_HUMAN, Protein DBF4 homolog A, ZDBF1.

Background: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.

Gen-ID: 10926

Pathways: Mitotic G1-G1/S Phases, DNA Replication