ELAC2 Antikörper (AA 88-190) (AbBy Fluor® 488)
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- Target Alle ELAC2 Antikörper anzeigen
- ELAC2 (ElaC Homolog 2 (ELAC2))
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Bindungsspezifität
- AA 88-190
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ELAC2 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ELAC2
- Isotyp
- IgG
- Top Product
- Discover our top product ELAC2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ELAC2 (ElaC Homolog 2 (ELAC2))
- Andere Bezeichnung
- ELAC2 (ELAC2 Produkte)
- Synonyme
- 1110017O07Rik antikoerper, D11Wsu80e antikoerper, Hpc2 antikoerper, ELC2 antikoerper, HPC2 antikoerper, elaC ribonuclease Z 2 antikoerper, ELAC2 antikoerper, Elac2 antikoerper
- Hintergrund
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Synonyms: elaC homolog 2, ElaC homolog protein 2, ELC2, Heredity prostate cancer protein 2, HPC2, putative prostate cancer susceptibility protein HPC2/ELAC2, Ribonuclease Z2, RNase Z2, tRNA 3 endonuclease 2, tRNase Z long form, tRNase Z2, Zinc phosphodiesterase ELAC protein 2.
Background: ELAC2 is a zinc phosphodiesterase which displays some tRNA 3' processing endonuclease activity. It is thought to be involved in tRNA maturation, acting by removing a 3' trailer from precursor tRNA. ELAC2 also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. A number of allelic variants have been investigated in hereditary prostate cancer.
- Gen-ID
- 60528
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