FAM3C Antikörper (AA 151-227) (AbBy Fluor® 350)
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- Target Alle FAM3C Antikörper anzeigen
- FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
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Bindungsspezifität
- AA 151-227
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FAM3C Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Ratte
- Homologie
- Mouse,Dog,Cow,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FAM3C
- Isotyp
- IgG
- Top Product
- Discover our top product FAM3C Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
- Andere Bezeichnung
- FAM3C (FAM3C Produkte)
- Synonyme
- ILEI antikoerper, D6Wsu176e antikoerper, Ilei antikoerper, wu:fb99h11 antikoerper, wu:fi35h03 antikoerper, zgc:55444 antikoerper, zgc:77090 antikoerper, family with sequence similarity 3 member C antikoerper, family with sequence similarity 3, member C antikoerper, family with sequence similarity 3 member C L homeolog antikoerper, fam3c antikoerper, FAM3C antikoerper, Fam3c antikoerper, fam3c.L antikoerper
- Hintergrund
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Synonyms: Fam3c, FAM3C_HUMAN, family with sequence similarity 3, member C, GS3786,ILEI, Interleukin-like EMT inducer, Predicted osteoblast protein, Protein FAM3C.
Background: ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
- Gen-ID
- 10447
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