HMGCL Antikörper (AA 41-140) (AbBy Fluor® 555)

Produktnummer ABIN901011

Produktdetails anti-HMGCL Antikörper (AbBy Fluor® 555)

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Bindungsspezifität: AA 41-140

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGCL Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HMGCL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HMGCL

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Andere Bezeichnung: HMGCL (HMGCL Produkte)

Hintergrund:

Synonyms: 3 hydroxy 3 methylglutaryl CoA lyase, 3 hydroxy 3 methylglutaryl Coenzyme A lyase, 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase hydroxymethylglutaricaciduria, 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase, 3-hydroxy-3-methylglutarate-CoA lyase, HL, HMG CoA lyase, HMG CoA Lyase Deficiency, HMG-CoA lyase, HMGCL, HMGCL_HUMAN, Hydroxymethylglutaricaciduria, Hydroxymethylglutaryl CoA lyase, Hydroxymethylglutaryl CoA lyase mitochondrial, Hydroxymethylglutaryl-CoA lyase, mitochondrial, MS725, OTTHUMP00000044830.

Background: Hydroxymethylglutaryl-CoA lyase (HMGCL) is found in fibroblasts, liver and lymphoblasts. It has a role in ketogenesis and leucine catabolism. Defects in HMGCL are the cause of 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (hydroxymethylglutaricaciduria), an autosomal recessive disease which can lead to hypoglycemia and coma.

Gen-ID: 2835