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IER3 Antikörper (AA 85-156) (AbBy Fluor® 488)

IER3 Reaktivität: Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN901738
  • Target Alle IER3 Antikörper anzeigen
    IER3 (Immediate Early Response 3 (IER3))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    AA 85-156
    Reaktivität
    • 33
    • 18
    • 15
    • 4
    • 4
    • 4
    Ratte
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IER3 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 36
    • 20
    • 14
    • 14
    • 13
    • 12
    • 12
    • 6
    • 6
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein
    Isotyp
    IgG
    Top Product
    Discover our top product IER3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    IER3 (Immediate Early Response 3 (IER3))
    Andere Bezeichnung
    IEX1 (IER3 Produkte)
    Synonyme
    DIF-2 antikoerper, DIF2 antikoerper, GLY96 antikoerper, IEX-1 antikoerper, IEX-1L antikoerper, IEX1 antikoerper, PRG1 antikoerper, AI663993 antikoerper, cI-3 antikoerper, gly96 antikoerper, IER3 antikoerper, Dif2 antikoerper, Iex1 antikoerper, Ler3 antikoerper, Prg1 antikoerper, immediate early response 3 antikoerper, IER3 antikoerper, Ier3 antikoerper
    Hintergrund

    Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3

    Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

    Gen-ID
    8870
    UniProt
    P46695
    Pathways
    Regulation of Carbohydrate Metabolic Process
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