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Importin 9 Antikörper (AA 601-729) (Biotin)

IPO9 Reaktivität: Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN902692
  • Target Alle Importin 9 (IPO9) Antikörper anzeigen
    Importin 9 (IPO9)
    Bindungsspezifität
    • 14
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-729
    Reaktivität
    • 44
    • 35
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 51
    • 6
    • 1
    Kaninchen
    Klonalität
    • 50
    • 8
    Polyklonal
    Konjugat
    • 31
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Importin 9 Antikörper ist konjugiert mit Biotin
    Applikation
    • 48
    • 18
    • 15
    • 13
    • 13
    • 11
    • 8
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Importin 9
    Isotyp
    IgG
    Top Product
    Discover our top product IPO9 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Importin 9 (IPO9)
    Andere Bezeichnung
    Importin 9 (IPO9 Produkte)
    Hintergrund

    Synonyms: B cell antigen receptor Ig beta associated protein 1, BPM 90, BPM L, BPM-L, BPM90, BPML, IBAP 1, Imp 9, Importin 9, Importin9, Importin-9, Novel centrosomal protein RanBPM, RAN binding protein 9, Ran binding protein centrosomal, Ran binding protein M, Ran BP9, Ran-binding protein 9, Ran-binding protein M, RANB9_HUMAN, RanBP 7, RANBP 9, RanBP7, RanBP9, RanBPM.

    Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.Tissue specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.

    Gen-ID
    10048
    Pathways
    Protein targeting to Nucleus
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