IRGM Antikörper (AA 51-150) (AbBy Fluor® 647)
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- Target Alle IRGM Antikörper anzeigen
- IRGM (Immunity-Related GTPase Family, M (IRGM))
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Bindungsspezifität
- AA 51-150
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IRGM Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IRGM
- Isotyp
- IgG
- Top Product
- Discover our top product IRGM Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IRGM (Immunity-Related GTPase Family, M (IRGM))
- Andere Bezeichnung
- IRGM (IRGM Produkte)
- Synonyme
- Ifi1 antikoerper, Iigp3 antikoerper, Iipg3 antikoerper, Irgm antikoerper, LRG-47 antikoerper, IFI1 antikoerper, IRGM1 antikoerper, LRG47 antikoerper, immunity-related GTPase family M member 1 antikoerper, immunity-related GTPase M antikoerper, immunity related GTPase M antikoerper, immunity-related GTPase family M protein antikoerper, Irgm1 antikoerper, Irgm antikoerper, IRGM antikoerper, LOC481473 antikoerper
- Hintergrund
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Synonyms: Irgm, I1, Iigp3, Immunity related GTPase family M protein 1, Immunity related GTPase family, M, Interferon inducible protein 1, IRGM1, LRG 47, LRG47, IRGM_HUMAN.
Background: IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathogens. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli.
- Gen-ID
- 345611
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