KIFC1 Antikörper (AbBy Fluor® 647)

Produktnummer ABIN903732

Produktdetails anti-KIFC1 Antikörper (AbBy Fluor® 647)

Target: KIFC1 (Kinesin Family Member C1 (KIFC1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIFC1 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Spezifität: Excitation / Emission Wavelengths: 652nm/668nm

Kreuzreaktivität: Ratte (Rattus), Schwein, Rind (Kuh)

Aufreinigung: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human KIFC1

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4 °C for 12 months

Haltbarkeit: 12 months

Details zu KIFC1

Target: KIFC1 (Kinesin Family Member C1 (KIFC1))

Andere Bezeichnung: KIFC1 (KIFC1 Produkte)

Hintergrund: The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIFC1 is a 673 amino acid protein that belongs to the kinesin-like family of proteins. KIFC1 localizes to the nucleus and contains a C-terminal kinesin-motor domain. Functioning as a minus-end directed microtubule-dependent motor, KIFC1 works together with NuMA and cytoplasmic Dynein to organize microtubule minus ends at spindle poles. HeLa cells deficient in KIFC1 exhibit multipolar mitotic spindles, suggesting that KIFC1 is essential for bipolar spindle formation.

Molekulargewicht: 74kDa

Gen-ID: 3833