KLHL13 Antikörper (AA 351-450) (Cy7)
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- Target Alle KLHL13 Antikörper anzeigen
- KLHL13 (Kelch-Like 13 (KLHL13))
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Bindungsspezifität
- AA 351-450
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Reaktivität
- Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KLHL13 Antikörper ist konjugiert mit Cy7
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Zebrafisch (Danio rerio)
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human KLHL13
- Isotyp
- IgG
- Top Product
- Discover our top product KLHL13 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- KLHL13 (Kelch-Like 13 (KLHL13))
- Andere Bezeichnung
- KLHL13 (KLHL13 Produkte)
- Synonyme
- 1200009K10Rik antikoerper, AI451128 antikoerper, Bklhd2 antikoerper, D130072F20Rik antikoerper, mKIAA1309 antikoerper, BKLHD2 antikoerper, Kelch-like protein 13 antikoerper, kelch-like 13 antikoerper, kelch like family member 13 antikoerper, kelch like family member 9 antikoerper, kelch-like family member 13 antikoerper, klh13 antikoerper, Klhl13 antikoerper, KLHL13 antikoerper, KLHL9 antikoerper
- Hintergrund
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Synonyms: Kelch-like protein 13, BTB and kelch domain-containing protein 2, KLH13_HUMAN.
Background: KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.
- Gen-ID
- 90293
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