Lipin 1 Antikörper (AA 501-600) (AbBy Fluor® 350)
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- Target Alle Lipin 1 (LPIN1) Antikörper anzeigen
- Lipin 1 (LPIN1)
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Bindungsspezifität
- AA 501-600
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Lipin 1 Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Rabbit,Chimpanzee,Goose
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Lipin 1
- Isotyp
- IgG
- Top Product
- Discover our top product LPIN1 Primärantikörper
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anti-Lipin 1 (LPIN1) (AA 729-924) antibody
LPIN1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 741-890) antibodyLPIN1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 201-300) antibodyLPIN1 Reaktivität: Ratte, Maus IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 792-890) antibodyLPIN1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3D9 unconjugated
anti-Lipin 1 (LPIN1) (AA 218-267) antibodyLPIN1 Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Fledermaus, Hamster, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 241-340) antibodyLPIN1 Reaktivität: Ratte, Maus IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 501-600) antibodyLPIN1 Reaktivität: Ratte IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 741-890) antibodyLPIN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (N-Term) antibodyLPIN1 Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schwein, Saccharomyces cerevisiae, Schaf, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Lipin 1 (LPIN1) (AA 300-400), (Internal Region) antibodyLPIN1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Lipin 1 (LPIN1)
- Andere Bezeichnung
- Lipin 1 (LPIN1 Produkte)
- Hintergrund
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Synonyms: KIAA0188, LPIN1, PAP1, Phosphatidate phosphatase LPIN1, LPIN1_HUMAN.
Background: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
- Gen-ID
- 23175
- Pathways
- Monocarboxylic Acid Catabolic Process
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