Myosin VIIA Antikörper (AA 851-950) (AbBy Fluor® 488)

Produktnummer ABIN907513

Produktdetails anti-Myosin VIIA Antikörper (AbBy Fluor® 488)

Target: Myosin VIIA (MYO7A)

Bindungsspezifität: AA 851-950

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin VIIA Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Myosin VIIa

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Myosin VIIA

Target: Myosin VIIA (MYO7A)

Andere Bezeichnung: Myosin 7a (MYO7A Produkte)

Synonyme: 53D10S antikoerper, BG:DS00929.11 antikoerper, CG7595 antikoerper, D antikoerper, D2 antikoerper, DM7a antikoerper, DMyoVIIa antikoerper, Dm 35B antikoerper, DmVIIA antikoerper, DmVIIa antikoerper, Dmel\\CG7595 antikoerper, Dro35B antikoerper, ESTS:53D10S antikoerper, Mhc35BC antikoerper, MyoVIIA antikoerper, anon-35Bb antikoerper, br27 antikoerper, ck/MyoVIIA antikoerper, l(1)35Ca antikoerper, l(2)07130 antikoerper, l(2)35Ca antikoerper, l(2)br27 antikoerper, l35Ca antikoerper, myoVIIA antikoerper, stc antikoerper, stch antikoerper, myo7a antikoerper, MYO7A antikoerper, NV17859 antikoerper, Hdb antikoerper, Myo7 antikoerper, USH1B antikoerper, nmf371 antikoerper, polka antikoerper, sh-1 antikoerper, sh1 antikoerper, DFNA11 antikoerper, DFNB2 antikoerper, MYOVIIA antikoerper, MYU7A antikoerper, NSRD2 antikoerper, crinkled antikoerper, myosin VIIAa antikoerper, myosin VIIa antikoerper, myosin VIIA antikoerper, myosin 7A antikoerper, myosin-VIIa antikoerper, ck antikoerper, myo7aa antikoerper, LOAG_02192 antikoerper, MYO7A antikoerper, myo7a antikoerper, LOC663995 antikoerper, LOC100116446 antikoerper, Myo7a antikoerper

Hintergrund:

Synonyms: DFNB2, MYU7A, NSRD2, USH1B, DFNA11, MYOVIIA, Unconventional myosin-VIIa, MYO7A

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Gen-ID: 4647

UniProt: Q13402

Pathways: Sensory Perception of Sound