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NCKAP1 Antikörper (AA 1001-1132) (AbBy Fluor® 488)

NCKAP1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN907759
  • Target Alle NCKAP1 Antikörper anzeigen
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1001-1132
    Reaktivität
    • 33
    • 26
    • 11
    Maus
    Wirt
    • 46
    • 1
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NCKAP1 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 36
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NCKAP1L
    Isotyp
    IgG
    Top Product
    Discover our top product NCKAP1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    Andere Bezeichnung
    NCKAP1 (NCKAP1 Produkte)
    Synonyme
    HEM2 antikoerper, NAP1 antikoerper, NAP125 antikoerper, p125Nap1 antikoerper, C79304 antikoerper, H19 antikoerper, Hem-2 antikoerper, Hem2 antikoerper, Nap1 antikoerper, mKIAA0587 antikoerper, mh19 antikoerper, NCK associated protein 1 antikoerper, NCK-associated protein 1 antikoerper, NCK-associated protein 1 L homeolog antikoerper, NCKAP1 antikoerper, Nckap1 antikoerper, nckap1.L antikoerper
    Hintergrund

    Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.

    Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

    Gen-ID
    10787
    UniProt
    P55160
    Pathways
    RTK Signalweg, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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