NCKAP1 Antikörper (AA 1001-1132) (AbBy Fluor® 350)

Produktnummer ABIN907763

Produktdetails anti-NCKAP1 Antikörper (AbBy Fluor® 350)

Target: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Bindungsspezifität: AA 1001-1132

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCKAP1 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCKAP1L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NCKAP1

Target: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Andere Bezeichnung: NCKAP1 (NCKAP1 Produkte)

Synonyme: HEM2 antikoerper, NAP1 antikoerper, NAP125 antikoerper, p125Nap1 antikoerper, C79304 antikoerper, H19 antikoerper, Hem-2 antikoerper, Hem2 antikoerper, Nap1 antikoerper, mKIAA0587 antikoerper, mh19 antikoerper, NCK associated protein 1 antikoerper, NCK-associated protein 1 antikoerper, NCK-associated protein 1 L homeolog antikoerper, NCKAP1 antikoerper, Nckap1 antikoerper, nckap1.L antikoerper

Hintergrund:

Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.

Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

Gen-ID: 10787

UniProt: P55160

Pathways: RTK Signalweg, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis