Nicastrin Antikörper (AA 21-120) (AbBy Fluor® 350)
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- Target Alle Nicastrin (NCSTN) Antikörper anzeigen
- Nicastrin (NCSTN)
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Bindungsspezifität
- AA 21-120
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Nicastrin Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Cow,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Nicastrin
- Isotyp
- IgG
- Top Product
- Discover our top product NCSTN Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Nicastrin (NCSTN)
- Andere Bezeichnung
- Nicastrin (NCSTN Produkte)
- Hintergrund
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Synonyms: ATAG1874, Nicastrin, NCSTN, KIAA0253, UNQ1874/PRO4317
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
- Gen-ID
- 23385
- UniProt
- Q92542
- Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
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