NOC2L Antikörper (AA 251-350) (Biotin)

Produktnummer ABIN908585

Produktdetails anti-NOC2L Antikörper (Biotin)

Target: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Bindungsspezifität: AA 251-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOC2L Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOC2L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NOC2L

Target: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Andere Bezeichnung: NOC2L (NOC2L Produkte)

Synonyme: NET15 antikoerper, NET7 antikoerper, NIR antikoerper, AA410003 antikoerper, AF155546 antikoerper, RGD1309387 antikoerper, NOC2 like nucleolar associated transcriptional repressor antikoerper, NOC2-like nucleolar associated transcriptional repressor antikoerper, NOC2L antikoerper, Noc2l antikoerper

Hintergrund:

Synonyms: NIR, NOC2 like, Novel INHAT inhibitor of histone acetyltransferase repressor, Nucleolar complex associated 2 homolog S. cerevisiae, Protein NOC2 homolog, NOC2L_HUMAN.

Background: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.

Gen-ID: 26155

Pathways: Negative Regulation of intrinsic apoptotic Signaling