TSPO Antikörper (AA 31-130) (AbBy Fluor® 350)
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- Target Alle TSPO Antikörper anzeigen
- TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))
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Bindungsspezifität
- AA 31-130
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TSPO Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Peripheral type Benzodiazepine Receptor
- Isotyp
- IgG
- Top Product
- Discover our top product TSPO Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))
- Andere Bezeichnung
- PBR (TSPO Produkte)
- Synonyme
- LOC732875 antikoerper, LOC100136652 antikoerper, LOC100280949 antikoerper, BZRP antikoerper, TSPO antikoerper, Bzrp antikoerper, IBP antikoerper, PBR antikoerper, Tspo1 antikoerper, MBR antikoerper, PTBZR02 antikoerper, Ptbzr antikoerper, RATPTBZR02 antikoerper, BPBS antikoerper, DBI antikoerper, PBS antikoerper, PKBS antikoerper, PTBR antikoerper, mDRC antikoerper, pk18 antikoerper, peripheral-type benzodiazepine receptor antikoerper, Peripheral-type benzodiazepine receptor antikoerper, putative peripheral-type benzodiazepine receptor antikoerper, translocator protein antikoerper, translocator protein homolog antikoerper, hypothetical protein antikoerper, LOC732875 antikoerper, MAV_3896 antikoerper, xccb100_2086 antikoerper, Smp_102510 antikoerper, Sros_1911 antikoerper, tspo antikoerper, LOC100280949 antikoerper, PGTG_16395 antikoerper, TSPO antikoerper, Tspo antikoerper
- Hintergrund
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Synonyms: BPBS, BZRP, DBI, IBP, Isoquinoline carboxamide-binding protein, MBR, mDRC, Mitochondrial benzodiazepine receptor, PBR, PBS, Peripheral benzodiazepine receptor, Peripheral benzodiazepine receptor-related protein, Peripheral type benzodiazepine receptor, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, translocator protein 18 kDa, Translocator protein, TSPO, Tspo1, Benzodiazapine receptor peripheral, Benzodiazepine peripheral binding site.
Background: PBR (Peripheral type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid producing tissues and is found in association with a 34 kDa voltage dependent anion channel protein (VDAC). PBR interacts with some benzodiazepines and has different affinities than its endogenous counterpart. PBR appears to be a key factor in the transport of cholesterol from the outer to the inner mitochondrial membrane to permit the initiation of steroid hormone synthesis. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis. It is speculated that patients with congenital lipoid adrenal hyperplasia, who cannot make any steroids, might have a genetic lesion in BZRP. A short form, PBRS is also expressed in the same tissues, but at a level about ten times that of PBR.
- Gen-ID
- 1622
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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