PCDHB13 Antikörper (AA 151-250) (AbBy Fluor® 488)

Produktnummer ABIN910252

Produktdetails anti-PCDHB13 Antikörper (AbBy Fluor® 488)

Target: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Bindungsspezifität: AA 151-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHB13 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PCDHB13

Target: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Andere Bezeichnung: PCDHB13 (PCDHB13 Produkte)

Synonyme: PCDH-BETA13 antikoerper, Pcdh3 antikoerper, Pcdbh6 antikoerper, PcdhbM antikoerper, PCDHB13 antikoerper, protocadherin beta 13 antikoerper, protocadherin beta 12 antikoerper, protocadherin beta-8 antikoerper, PCDHB13 antikoerper, Pcdhb12 antikoerper, Pcdhb13 antikoerper, LOC518612 antikoerper

Hintergrund:

Synonyms: Protocadherin beta 13, PCDH BETA13, PCDHB13, PCDBD_HUMAN

Background: Cadherins are calcium-dependent cell-cell adhesion molecules, and protocadherins constitute a subfamily of nonclassic cadherins. Protocadherin beta 13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Gen-ID: 56123