PHKB Antikörper (AA 45-160) (AbBy Fluor® 555)
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- Target Alle PHKB Antikörper anzeigen
- PHKB (Phosphorylase Kinase, beta (PHKB))
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Bindungsspezifität
- AA 45-160
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PHKB Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PHKB
- Isotyp
- IgG
- Top Product
- Discover our top product PHKB Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PHKB (Phosphorylase Kinase, beta (PHKB))
- Andere Bezeichnung
- PHKB (PHKB Produkte)
- Synonyme
- AI463271 antikoerper, phosphorylase kinase regulatory subunit beta antikoerper, phosphorylase kinase beta antikoerper, PHKB antikoerper, Phkb antikoerper
- Hintergrund
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Synonyms: Phosphorylase B, Phosphorylase kinase B, Phosphorylase kinase beta polypeptide, Phosphorylase kinase beta subunit, DKFZp781E15103, FLJ41698, KPBB_HUMAN.
Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010].
- Gen-ID
- 5257
- Pathways
- Cellular Glucan Metabolic Process
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