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PLCz1 Antikörper (AA 351-450) (AbBy Fluor® 488)

PLCz1 Reaktivität: Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN911374
  • Target Alle PLCz1 Antikörper anzeigen
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Bindungsspezifität
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 20
    • 14
    • 4
    Ratte
    Wirt
    • 33
    • 2
    Kaninchen
    Klonalität
    • 33
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PLCz1 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 12
    • 12
    • 12
    • 10
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PLCZ1
    Isotyp
    IgG
    Top Product
    Discover our top product PLCz1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Andere Bezeichnung
    PLCZ1 (PLCz1 Produkte)
    Synonyme
    PLC-zeta-1 antikoerper, PLCZ1 antikoerper, 1700041H07Rik antikoerper, PLCzeta antikoerper, NYD-SP27 antikoerper, PLCZ antikoerper, phospholipase C zeta 1 antikoerper, phospholipase C, zeta 1 antikoerper, PLCZ1 antikoerper, Plcz1 antikoerper
    Hintergrund

    Synonyms: PLCzeta, NYD-SP27, PLC-zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, Testis-development protein NYD-SP27, PLCZ1, PLCZ1_HUMAN

    Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

    Gen-ID
    89869
    UniProt
    Q86YW0
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