PLSCR3 Antikörper (AA 201-295) (AbBy Fluor® 350)

Produktnummer ABIN911538

Produktdetails anti-PLSCR3 Antikörper (AbBy Fluor® 350)

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Bindungsspezifität: AA 201-295

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLSCR3 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLSCR3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PLSCR3

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Andere Bezeichnung: PLSCR3 (PLSCR3 Produkte)

Synonyme: 2210403O21Rik antikoerper, 2610037N06Rik antikoerper, ESTM3 antikoerper, X83310 antikoerper, Pls3 antikoerper, zgc:77051 antikoerper, phospholipid scramblase 3 antikoerper, phospholipid scramblase 3b antikoerper, PLSCR3 antikoerper, Plscr3 antikoerper, plscr3b antikoerper

Hintergrund:

Synonyms: Ca2+-dependent phospholipid scramblase 3, Phospholipid scramblase 3, PL scramblase 3, PLS3, PLS3_HUMAN.

Background: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Gen-ID: 57048

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis