PNKP Antikörper (AA 51-160) (AbBy Fluor® 488)

Produktnummer ABIN911592

Produktdetails anti-PNKP Antikörper (AbBy Fluor® 488)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Bindungsspezifität: AA 51-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNKP Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PNK1/PNKP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Andere Bezeichnung: PNK1/PNKP (PNKP Produkte)

Synonyme: EIEE10 antikoerper, MCSZ antikoerper, PNK antikoerper, Tb06.28P18.320 antikoerper, 21.m03011 antikoerper, 1810009G08Rik antikoerper, polynucleotide kinase 3'-phosphatase antikoerper, hypothetical protein antikoerper, polynucleotide kinase 3'- phosphatase antikoerper, PNKP antikoerper, Pnkp antikoerper, Tc00.1047053507017.50 antikoerper, Tc00.1047053505807.190 antikoerper, Tb927.6.1580 antikoerper, BBOV_IV000690 antikoerper, CC1G_05202 antikoerper, PGTG_20262 antikoerper, PGTG_18987 antikoerper, pnkp.S antikoerper, pnkp antikoerper

Hintergrund:

Synonyms: Bunctional polynucleotide phosphatase/kinase, DEM 1, DEM1, DNA 5' kinase/3' phosphatase, PNK 1, PNK, PNK1, PNKP, Polynucleotide 5' hydroxyl kinase, Polynucleotide kinase 3 prime phosphatase, Polynucleotide kinase 3' phosphatase, Polynucleotide Kinase, PNKP_HUMAN.

Background: Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage.PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.

Gen-ID: 11284

Pathways: DNA Reparatur, Nucleotide Phosphorylation