TMEM123 Antikörper (AA 101-180) (Biotin)

Produktnummer ABIN911738

Produktdetails anti-TMEM123 Antikörper (Biotin)

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Bindungsspezifität: AA 101-180

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM123 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Porimin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TMEM123

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Andere Bezeichnung: Porimin (TMEM123 Produkte)

Synonyme: KCT3 antikoerper, PORIMIN antikoerper, PORMIN antikoerper, 2310075C12Rik antikoerper, RGD1305625 antikoerper, kct3 antikoerper, pormin antikoerper, porimin antikoerper, transmembrane protein 123 antikoerper, transmembrane protein 123 L homeolog antikoerper, TMEM123 antikoerper, Tmem123 antikoerper, tmem123.L antikoerper, tmem123 antikoerper

Hintergrund:

Synonyms: KCT3, Keratinocytes associated transmembrane protein 3, Pro oncosis receptor inducing membrane injury, Serine/threonine rich receptor, TMEM123, Transmembrane protein 123, PORIM_HUMAN.

Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Gen-ID: 114908

Pathways: Regulation of Cell Size